Celluar pathology Assignment Example | Topics and Well Written Essays - 3000 words

Celluar pathology - Assignment ExampleBy studying the density of blood vass resulting fromevaluation (Nico et al. 2008). Nico in picky describes the issue of micro vessel or microvascular density as being the gold standard with respect to the morphological assessment of angiogenesis inIn addition to describing the physiological mechanisms, It is also realizable to make generalizations concerning high levels of angiogenesis and specific types of carcinomas, specifically cancers of the prostate or the summits characterized by high levels of micro vessel formation. Considerable research has been devoted to the characterization of front cancer, with confirmation of the importance and predictive power of angiogenesis in the tumorigenesis process. There is considerable support for the utility of micro vessel density analysis as a predictive methodology for these tumors, with historic evidence that angiogenesis precedes the malignant transformation of mammary cells into fully cancerou s carcinomas arising from relatively benign papillomas.(Srivastava et al. 1988). There is little doubt that higher(prenominal) rates of angiogenesis do indeed correlate with the emergence of certain(a) tumors, but at present the connection may not be absolute breast cancerstudies indicate that lesions with the highest amount of micro vessel density do carry the greatest risk of breast cancer, but it is not entirely certain whether there is an absolute threshold of densitythat transfection of cancerous tissue with factors antagonistic to angiogenesis decrease the hazard of further growth and malignancy (Miller & Sledge, 2003). This is compelling evidence describingparticular mutation of a particular oncogene. As cells continuously grow and divide in the millions over many years, each replication event creates a probability that the right (or wrong) mutation willoccur in cells that already carry some growth irregularities. If this chain of mutations is not counteracted by surgical o r remediation methodologies, then